two aspartame (methanol, formaldehyde, formic acid...

tag:blogger.com,1999:blog-6950106.post-41688245991543758642008-06-25T06:54:00.000Z2008-06-25T06:54:00.000Z2008-06-25T06:54:00.000Ztwo aspartame (methanol, formaldehyde, formic acid...two aspartame (methanol, formaldehyde, formic acid) toxicity research studies by Resia Pretorius, U. Pretoria, South Africa, debate with JD Fernstrom: Murray 2008.04.04 2008.05.13 http://rmforall.blogspot.com/2008_04_01_archive.htm Friday, April 4, 2008 http://groups.yahoo.com/group/aspartameNM/message/1536 ____________________________________________________ [ Re: http://www.newswise.com/p/articles/view/540434/ Mayo Clinic Women's HealthService 2008.05.06 "... Currently, the FDA approves these low-calorie sweeteners: -- Aspartame (Equal, NutraSweet). However, aspartame isn't safe for people who have phenylketonuria (PKU), a rare hereditary disease. " ] "Of course, everyone chooses, as a natural priority, to enjoy peace, joy, and love by helping to find, quickly share, and positively act upon evidence about healthy and safe food, drink, and environment." Rich Murray, MA Room For All rmforall@comcast.net 505-501-2298 1943 Otowi Road, Santa Fe, New Mexico 87505 http://RMForAll.blogspot.com new primary archive http://groups.yahoo.com/group/aspartameNM/messages group with 125 members, 1,539 posts in a public archive http://groups.yahoo.com/group/aspartame/messages group with 1,096 members, 22,620 posts in a public archive ____________________________________________________ [ See also: methanol impurity in alcohol drinks [ and aspartame ] is turned into neurotoxic formic acid, prevented by folic acid, re Fetal Alcohol Syndrome, BM Kapur, DC Lehotay, PL Carlen at U. Toronto, Alc Clin Exp Res 2007 Dec. plain text: detailed biochemistry, CL Nie et al. 2007.07.18: Rich Murray 2008.02.24 http://rmforall.blogspot.com/2008_02_01_archive.htm Sunday, February 24, 2008 http://groups.yahoo.com/group/aspartameNM/message/1524 http://groups.yahoo.com/group/aspartameNM/message/782 Smith, Terpening, Schmidt, Gums: full text: aspartame, MSG, fibromyalgia: Murray 2002.01.17 Jerry D Smith, Chris M Terpening, Siegfried OF Schmidt, and John G Gums Relief of Fibromyalgia Symptoms Following Discontinuation of Dietary Excitotoxins. The Annals of Pharmacotherapy 2001; 35(6): 702-706. Malcolm Randall Veterans Affairs Medical Center, Gainesville, FL, USA. BACKGROUND: Fibromyalgia is a common rheumatologic disorder that is often difficult to treat effectively. CASE SUMMARY: Four patients diagnosed with fibromyalgia syndrome for two to 17 years are described. All had undergone multiple treatment modalities with limited success. All had complete, or nearly complete, resolution of their symptoms within months after eliminating monosodium glutamate (MSG) or MSG plus aspartame from their diet. All patients were women with multiple comorbidities prior to elimination of MSG. All have had recurrence of symptoms whenever MSG is ingested. Siegfried O. Schmidt, MD Asst. Clinical Prof. siggy@shands.ufl.edu Community Health and Family Medicine, U. Florida, Gainesville, FL Shands Hospital West Oak Clinic Gainesville, FL 32608-3629 352-376-5071 Avoiding formaldehyde allergic reactions in children, aspartame, vitamins, shampoo, conditioners, hair gel, baby wipes, Sharon E Jacob, MD, Tace Steele, U. Miami, Pediatric Annals 2007 Jan.: eyelid contact dermatitis, AM Hill, DV Belsito, 2003 Nov.: Murray 2008.03.27 http://rmforall.blogspot.com/2008_03_01_archive.htm Thursday, March 27, 2008 http://groups.yahoo.com/group/aspartameNM/message/1532 "It is generally recommended that exposure to products containing formaldehyde, FRP's, and aspartame (NutraSweet) be avoided in children." "Through metabolism, aspartame is converted metabolically in the liver to methanol, which is in turn metabolized to formaldehyde. 8" www.pediatricannalsonline.com/showPdf.asp?rID=21306 Avoiding formaldehyde allergic reactions in children Pediatric Annals. 2007 Jan.; 36(1): 55-6. PMID: 17269284 Sharon E. Jacob, MD, Director, Contact Dermatitis Clinic, Dept. of Dermatology and Cutaneous Surgery, U. of Miami, 1295 NW 14th St., Miami, FL 33125, fax 305-243-6191 formaldehyde from many sources, including aspartame, is major cause of Allergic Contact Dermatitis, SE Jacob, T Steele, G Rodriguez, Skin and Aging 2005 Dec.: Murray 2008.03.27 http://rmforall.blogspot.com/2008_03_01_archive.htm Thursday, March 27, 2008 http://groups.yahoo.com/group/aspartameNM/message/1533 Sharon E. Jacob, MD Assistant Professor of Medicine (Dermatology) University of California, San Diego 200 W. Arbor Drive #8420 San Diego, CA 92103-8420 Tel: 858-552-8585 ×3504 Fax: 305-675-8317 sjacob@contactderm.net; "For example, diet soda and yogurt containing aspartame (Nutrasweet), release formaldehyde in their natural biological degradation. One of aspartame's metabolites, aspartic acid methyl ester, is converted to methanol in the body, which is oxidized to formaldehyde in all organs, including the liver and eyes. 22 Patients with a contact dermatitis to formaldehyde have been seen to improve once aspartame is avoided. 22 Notably, the case that Hill and Belsito reported had a 6-month history of eyelid dermatitis that subsided after 1 week of avoiding diet soda. 22" "We present a case of a medical student who presented with erythematous eczematoid plaques on her trunk and legs and fine vesiculation of her scalp, 3 weeks after starting anatomy class. Of note, she routinely washed her face and arms after leaving the anatomy lab, but remained in her scrubs for the rest of the day. Formaldehyde and Quaternium-15 positive reactions in the same patient." "Our patient underscores the importance of appropriate patch testing and education. Once we identified the allergy to formaldehyde and quaternium-15, we provided patient education materials regarding the common and not-so-common locations of these chemicals and cross-reactors. We also gave the patient information on avoidance and safe alternatives (see Table 5). Fortunately, with technical advances, this student completed the anatomy section via electronic learning tools. By avoiding formaldehyde, including anatomy lab, FRP in her shampoo and cosmetics, and aspartame in her diet, this patient dramatically improved. As with all contact dermatitides, the mainstay of treatment for allergic contact dermatitis is avoidance." http://www.skinandaging.com/article/5158 Allergen Focus: Focus on T.R.U.E. Test Allergens #21, 13 and 18: Formaldehyde and Formaldehyde-Releasing Preservatives Skin & Aging, ISSN 1096-0120; 13(12) 2005 Dec.: 22-27. Sharon E. Jacob, M.D., Tace Steele, B.A., and Georgette Rodriguez, M.D., M.P.H. ] http://foodqualitynews.com/news/ng.asp?n=84424-aspartame-sweetener recent news re E Pretorius aspartame and brain review Direct and indirect cellular effects of aspartame on the brain. Humphries P, Pretorius E, Naude H, U. Pretoria, South Africa, Eur J Clin Nutr. 2007 Aug 8: Murray 2007.08.12 http://groups.yahoo.com/group/aspartameNM/message/1463 "The aim of this study was to discuss the direct and indirect cellular effects of aspartame on the brain, and we propose that excessive aspartame ingestion might be involved in the pathogenesis of certain mental disorders (DSM-IV-TR 2000) and also in compromised learning and emotional functioning." Eur J Clin Nutr. 2007 Aug 8; [Epub ahead of print] Direct and indirect cellular effects of aspartame on the brain. Humphries P, Pretorius E, resia.pretorius@up.ac.za; Naude H. [1] Department of Anatomy, University of Pretoria, Pretoria, Gauteng, South Africa [2] Department of Anatomy, University of the Limpopo, South Africa. The use of the artificial sweetener, aspartame, has long been contemplated and studied by various researchers, and people are concerned about its negative effects. Aspartame is composed of phenylalanine (50%), aspartic acid (40%) and methanol (10%). Phenylalanine plays an important role in neurotransmitter regulation, whereas aspartic acid is also thought to play a role as an excitatory neurotransmitter in the central nervous system. Glutamate, asparagines and glutamine are formed from their precursor, aspartic acid. Methanol, which forms 10% of the broken down product, is converted in the body to formate, which can either be excreted or can give rise to formaldehyde, diketopiperazine (a carcinogen) and a number of other highly toxic derivatives. Previously, it has been reported that consumption of aspartame could cause neurological and behavioural disturbances in sensitive individuals. Headaches, insomnia and seizures are also some of the neurological effects that have been encountered, and these may be accredited to changes in regional brain concentrations of catecholamines, which include norepinephrine, epinephrine and dopamine. The aim of this study was to discuss the direct and indirect cellular effects of aspartame on the brain, and we propose that excessive aspartame ingestion might be involved in the pathogenesis of certain mental disorders (DSM-IV-TR 2000) and also in compromised learning and emotional functioning. European Journal of Clinical Nutrition advance online publication, 8 August 2007; doi:10.1038/sj.ejcn.1602866. PMID: 17684524 Keywords: astrocytes; aspartame; neurotransmitters; glutamate; GABA; serotonin; dopamine; acetylcholine Received 25 October 2006; revised 26 April 2007; accepted 27 April 2007 Correspondence: Professor E Pretorius, Department of Anatomy, University of Pretoria, BMW Building, Dr Savage Street, PO Box 2034, Pretoria 0001, Gauteng, South Africa. E-mail: resia.pretorius@up.ac.za c 2007 Nature Publishing Group, All rights reserved 0954-3007/07 $30.00 www.nature.com/ejcn [ Figures 1-6 not included herein ] [ for more, use initial URL..... ]Rich Murrayhttp://www.blogger.com/profile/12048425723553171316noreply@blogger.com